Diallyl trisulfide inhibits monosodium urate-induced NLRP3 inflammasome activation via NOX3/4-dependent mitochondrial oxidative stress in RAW 264.7 and bone marrow-derived macrophages
Min Yeong Kim, EunJin Bang, Hyun Hwangbo, Seon Yeong Ji, Da Hye Kim, Hyesook Lee, Cheol Park, Su Hyun Hong, Gi‐Young Kim, Yung Hyun Choi, Gi‐Young Kim, Yung Hyun Choi
Topics & Concepts
InflammasomeDiallyl trisulfideChemistryReactive oxygen speciesOxidative stressTXNIPInflammationNADPH oxidaseBiochemistryCell biologyMolecular biologyPharmacologyBiologyReceptorImmunologyApoptosisThioredoxinGarlic and Onion StudiesGout, Hyperuricemia, Uric AcidInflammasome and immune disorders