Biodegradable Zn-0.8Mg-0.2Sr alloy as an internal fixation material exhibits controlled degradation with enhanced osteogenesis
Yuting Tian, Yichen Xu, Jan Pinc, Jaroslav Fojt, Vojtěch Hybášek, Jiří Kubásek, Šárka Msallamová, Yong Xiang, Min Guo, Jaroslav Čapek, Ping Li, Tao Hu
Abstract
studies confirmed favorable biocompatibility and more uniform degradation of Zn-0.8Mg-0.2Sr, with reduced pitting corrosion and structural collapse. Notably, Zn-0.8Mg-0.2Sr exhibited superior performance in promoting bone regeneration and anti-inflammatory immunomodulation compared to pure Zn. These findings highlight Zn-0.8Mg-0.2Sr as a promising alternative to conventional internal fixation materials, offering favorable biocompatibility, controlled biodegradability, and enhanced osteogenesis.
Topics & Concepts
Degradation (telecommunications)AlloyChemistryFixation (population genetics)Chemical engineeringMaterials scienceMetallurgyComputer scienceBiochemistryGeneTelecommunicationsEngineeringMagnesium Alloys: Properties and ApplicationsOrthopaedic implants and arthroplastyAluminum Alloys Composites Properties