BH3 mimetics selectively eliminate chemotherapy-induced senescent cells and improve response in TP53 wild-type breast cancer
Ashkan Shahbandi, Sonia G. Rao, Ashlyn Y. Anderson, Wesley D. Frey, Joy O. Olayiwola, Nathan Ungerleider, James G. Jackson
Topics & Concepts
ChemotherapyBreast cancerMCL1SenescenceCancer researchCancer cellCancerApoptosisMetastasisBiologyMedicineInternal medicineDownregulation and upregulationGeneBiochemistryTelomeres, Telomerase, and SenescenceCancer-related Molecular PathwaysCell death mechanisms and regulation