Triphenyl phosphate induces clastogenic effects potently in mammalian cells, human CYP1A2 and 2E1 being major activating enzymes
Jiayi Xie, Hongwei Tu, Yijing Chen, Zhihong Chen, Zongying Yang, Yungang Liu
Topics & Concepts
Micronucleus testMicronucleusGenotoxicityCYP1A2ClastogenChemistryMolecular biologyCYP2E1EnzymeBiochemistryCell cultureInducerBiologyCytochrome P450ToxicityGeneGeneticsOrganic chemistryCarcinogens and Genotoxicity AssessmentToxic Organic Pollutants ImpactEffects and risks of endocrine disrupting chemicals