Litcius/Paper detail

Enhancing plant biotechnology by nanoparticle delivery of nucleic acids

Jiaxi Yong, Miaomiao Wu, Bernard J. Carroll, Zhi Ping Xu, Run Zhang

2024Trends in Genetics41 citationsDOIOpen Access PDF

Abstract

Plant biotechnology plays a crucial role in developing modern agriculture and plant science research. However, the delivery of exogenous genetic material into plants has been a long-standing obstacle. Nanoparticle-based delivery systems are being established to address this limitation and are proving to be a feasible, versatile, and efficient approach to facilitate the internalization of functional RNA and DNA by plants. The nanoparticle-based delivery systems can also be designed for subcellular delivery and controlled release of the biomolecular cargo. In this review, we provide a concise overview of the recent advances in nanocarriers for the delivery of biomolecules into plants, with a specific focus on applications to enhance RNA interference, foreign gene transfer, and genome editing in plants.

Topics & Concepts

NanocarriersBiologyBiotechnologyComputational biologyRNA interferenceNucleic acidGene deliveryInternalizationRNANanotechnologyBiochemical engineeringDrug deliveryGeneGeneticsGenetic enhancementEngineeringMaterials scienceCellRNA Interference and Gene DeliveryChromosomal and Genetic VariationsCRISPR and Genetic Engineering