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Synthesis and preliminary evaluation of 211At-labeled inhibitors of prostate-specific membrane antigen for targeted alpha particle therapy of prostate cancer

Ganesan Vaidyanathan, Ronnie C. Mease, Il Minn, Jae‐Yeon Choi, Ying Chen, Hassan M. Shallal, Choong Mo Kang, Darryl McDougald, Vivek Kumar, Martin G. Pomper, Michael R. Zalutsky

2021Nuclear Medicine and Biology30 citationsDOIOpen Access PDF

Topics & Concepts

In vivoBiodistributionProstate cancerGlutamate carboxypeptidase IIChemistryRadionuclide therapyPotencyDOTAProstateLigand (biochemistry)In vitroLipophilicityCancerCancer researchPharmacologyBiochemistryMedicineReceptorInternal medicineBiologyBiotechnologyRadiopharmaceutical Chemistry and ApplicationsProstate Cancer Treatment and ResearchPeptidase Inhibition and Analysis
Synthesis and preliminary evaluation of 211At-labeled inhibitors of prostate-specific membrane antigen for targeted alpha particle therapy of prostate cancer | Litcius