Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4
Peng Xiao, Shengchao Guo, Xin Wen, Qing‐tao He, Hui Lin, Shen-Ming Huang, Lu Gou, Chao Zhang, Zhao Yang, Ya-Ni Zhong, Chuan-Cheng Yang, Li Yu, Zheng Gong, Xiao-Na Tao, Zhi-Shuai Yang, Yan Lü, Shaolong Li, Junyan He, Chuanxin Wang, Lei Zhang, Liangliang Kong, Jin‐Peng Sun, Xiao Yu
Topics & Concepts
G protein-coupled receptorProtein subunitTransmembrane domainTransmembrane proteinPeptideChemistryReceptorBiophysicsAgonistRational designStereochemistryBiochemistryCell biologyBiologyGeneticsGeneReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyMass Spectrometry Techniques and Applications