Total synthesis of<i>Lentinus giganteus</i>glycans with antitumor activities<i>via</i>stereoselective α-glycosylation and orthogonal one-pot glycosylation strategies
Yunqin Zhang, Yanlei Hu, Shanshan Liu, Haiqing He, Roujing Sun, Gang Lü, Guozhi Xiao
Abstract
Stereoselective and one-pot synthesis of Lentinus giganteus glycans with antitumor activities has been accomplished, which features a newly developed merging reagent modulation and remote anchimeric assistance (RMRAA) α-galactosylation strategy.
Topics & Concepts
StereoselectivityGlycosylationLentinusTotal synthesisChemistryGlycanReagentStereochemistryCombinatorial chemistryBiochemistryOrganic chemistryGlycoproteinCatalysisFood scienceMushroomCarbohydrate Chemistry and SynthesisMicrobial Natural Products and BiosynthesisGlycosylation and Glycoproteins Research