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Discovery of quinazoline HPK1 inhibitors with high cellular potency

Momar Toure, Theresa Johnson, Bin Li, Ralf Schmidt, H. Ma, Constantin Neagu, Andrea Unzue Lopez, Yanping Wang, Satenig Guler, Yufang Xiao, Renate Henkes, Kevin K.W. Ho, Susan Zhang, Chia Lin Chu, Uma Mahesh Gundra, Filippos Porichis, Long Li, Christine K. Maurer, Zhizhou Fang, Djordje Müsil, Maria DiPoto, Emily Friis, Reinaldo Jones, Christopher C. Jones, J. R. Cummings, Eugene L. Piatnitski Chekler, Eva Maria Tanzer, Bayard R. Huck, Brian Sherer

2023Bioorganic & Medicinal Chemistry13 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryImmune systemHaematopoiesisAcquired immune systemCytokinePD-L1Cancer researchCell biologyImmunotherapyImmunologyBiologyStem cellQuinazolinone synthesis and applicationsCAR-T cell therapy researchImmune Cell Function and Interaction
Discovery of quinazoline HPK1 inhibitors with high cellular potency | Litcius