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Sinonasal Inverted Papilloma and Squamous Cell Carcinoma: Contemporary Management and Patient Outcomes

Jacob G. Eide, Kevin C. Welch, Nithin D. Adappa, James N. Palmer, Charles C. L. Tong

2022Cancers39 citationsDOIOpen Access PDF

Abstract

Inverted papillomas (IP) are the most common sinonasal tumor with a tendency for recurrence, potential attachment to the orbit and skull base, and risk of malignant degeneration into squamous cell carcinoma (SCC). While the overall rate of recurrence has decreased with the widespread adoption of high-definition endoscopic optics and advanced surgical tools, there remain challenges in managing tumors that are multiply recurrent or involve vital neurovascular structures. Here, we review the state-of-the-art diagnostic tools for IP and IP-degenerated SCC, contemporary surgical management, and propose a surveillance protocol.

Topics & Concepts

Inverted papillomaNeurovascular bundleMedicineBasal cellMalignant transformationSkullPapillomaOrbit (dynamics)SurgeryPathologyAerospace engineeringEngineeringHead and Neck Surgical OncologySinusitis and nasal conditionsBone Tumor Diagnosis and Treatments
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