Intratumoral spatial heterogeneity of tumor-infiltrating lymphocytes is a significant factor for precisely stratifying prognostic immune subgroups of microsatellite instability-high colorectal carcinomas
Minsun Jung, Ji Ae Lee, Seungyeon Yoo, Jeong Mo Bae, Gyeong Hoon Kang, Jung Ho Kim
Topics & Concepts
Microsatellite instabilityTumor-infiltrating lymphocytesSpatial heterogeneityBiologyCD8Colorectal cancerTumour heterogeneityImmune systemOncologyGenetic heterogeneityCancer researchInternal medicineCancerPathologyMedicineImmunologyGeneMicrosatelliteGeneticsAlleleEcologyPhenotypeCancer Immunotherapy and BiomarkersGenetic factors in colorectal cancerColorectal Cancer Screening and Detection