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Reduction in Sporadic Norovirus Infections Following the Start of the COVID-19 Pandemic, 2019–2020, Philadelphia

Irving Nachamkin, Melissa Richard‐Greenblatt, Mei Yu, Hong‐Thuy Bui

2021Infectious Diseases and Therapy23 citationsDOIOpen Access PDF

Abstract

INTRODUCTION: Norovirus infections are common in the USA and worldwide. Detection of norovirus in fecal samples is now common in routine tests for enteric pathogens using molecular methods. We observed a change in positivity rates for norovirus after the beginning of the coronavirus disease 2019 (COVID-19) pandemic in our laboratory and performed a more detailed analysis of testing results. METHODS: We reviewed the positivity rates for detection of common enteric pathogens from stool samples submitted to an academic medical center laboratory pre (2016-2019) and post the start of the COVID-19 pandemic (2020). RESULTS: In contrast to other enteric pathogens, norovirus positivity rates dropped dramatically from a yearly average of 3.9% in 2016-2019 to 0.76% from March 2020 through the end of 2020. CONCLUSION: A sustained reduction in norovirus positivity rates was temporally associated with COVID-19 mitigation processes in the Philadelphia area, while positivity rates for other common enteric pathogens were only intermittently reduced.

Topics & Concepts

NorovirusPandemicMedicineCoronavirus disease 2019 (COVID-19)FecesVirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Acute gastroenteritisMicrobiologyOutbreakDiseaseInternal medicineBiologyInfectious disease (medical specialty)Viral gastroenteritis research and epidemiologyClostridium difficile and Clostridium perfringens researchRespiratory viral infections research