Electrochemical determination of captopril using a disposable graphite electrode modified with a molecularly imprinted film, accompanied by a ratiometric read-out
Ahmed Z. Alanazi, Khalid Alhazzani, Hossieny Ibrahim, Al‐Montaser Bellah H. Ali, Mahmoud Darweesh, Mohamed M. El‐Wekil
Abstract
) increased linearly with increasing captopril concentration in the range of 1-450 nM, with a detection limit (S/N = 3) of 0.3 nM. The ratiometric-based MIP electrochemical platform (Cu-MIP/NS-PC@Ag/GE) was successfully applied to detect captopril in complex matrices such as tablets, serum, and urine samples. This platform holds promise for sensitive and selective detection of captopril in various practical applications.
Topics & Concepts
CaptoprilGraphiteElectrochemistryElectrodeChemistryChromatographyMaterials scienceOrganic chemistryMedicinePhysical chemistryInternal medicineBlood pressureElectrochemical sensors and biosensorsAnalytical Chemistry and SensorsElectrochemical Analysis and Applications