Non-invasive diagnosis of acute kidney injury using Mn-doped carbon dots-based magnetic resonance imaging
Xingtai Huang, Zihan Wang, Shujie Li, Shiqi Lin, Lirong Zhang, Zhaowei Meng, Xuejun Zhang, Shao‐Kai Sun
Abstract
), which can produce effective positive enhancement in the kidneys and clearly show the fine structures of the kidneys including the cortex, outer medulla, and inner medulla. In an acute kidney injury model, Mn-CDs-based CE-MRI can not only accurately and intuitively reveal the site of kidney injury consistent with the pathological analysis, but also reflect the functional changes in the injured kidney. Collectively, our study provides a new strategy for the non-invasive diagnosis of acute kidney injury using CE-MRI based on Mn-CDs.
Topics & Concepts
Magnetic resonance imagingNuclear magnetic resonanceAcute kidney injuryKidneyChemistryMaterials scienceMedicineRadiologyPhysicsInternal medicineCarbon and Quantum Dots ApplicationsLanthanide and Transition Metal ComplexesNanoplatforms for cancer theranostics