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Photoredox-catalyzed coupling of aryl sulfonium salts with CO<sub>2</sub>and amines to access<i>O</i>-aryl carbamates

Yanhui Guo, Wei Li, Zhonglin Wen, Huanfeng Jiang, Chaorong Qi

2022Chemical Communications31 citationsDOI

Abstract

a site-selective thianthrenation/carbamoyloxylation two-step process. Mild conditions, broad substrate scope and good functional group tolerance are the features of the transformation. The synthetic utility of the method was demonstrated by the late-stage modification of bioactive molecules and pharmaceuticals.

Topics & Concepts

ArylSulfoniumChemistryCatalysisCombinatorial chemistrySubstrate (aquarium)Functional groupSalt (chemistry)Photoredox catalysisDiazoMoleculeCoupling reactionOrganic chemistryAlkylPhotocatalysisPolymerGeologyOceanographyCarbon dioxide utilization in catalysisSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods
Photoredox-catalyzed coupling of aryl sulfonium salts with CO<sub>2</sub>and amines to access<i>O</i>-aryl carbamates | Litcius