Transient secretion of VEGF protein from transplanted hiPSC-CMs enhances engraftment and improves rat heart function post MI
Xuefeng Ai, Bingqian Yan, Nevin Witman, Yiqi Gong, Yang Li, Yao Tan, Ying Chen, Minglu Liu, Tingting Lu, Runjiao Luo, Huijing Wang, Kenneth R. Chien, Wei Wang, Wei Fu
Topics & Concepts
Protein kinase BPI3K/AKT/mTOR pathwayVascular endothelial growth factorTransplantationBiologyInduced pluripotent stem cellCell biologyKEGGRegeneration (biology)Vascular endothelial growth factor ACancer researchSignal transductionTranscriptomeMedicineGene expressionInternal medicineVEGF receptorsEmbryonic stem cellGeneBiochemistryTissue Engineering and Regenerative MedicineElectrospun Nanofibers in Biomedical ApplicationsRNA Interference and Gene Delivery