Structural and functional diversity among agonist-bound states of the GLP-1 receptor
Brian P. Cary, Giuseppe Deganutti, Peishen Zhao, Tin T. Truong, Sarah Piper, Xinyu Liu, Matthew J. Belousoff, Radostin Danev, Patrick M. Sexton, Denise Wootten, Samuel H. Gellman
Topics & Concepts
AgonistG protein-coupled receptorReceptorPeptideBiophysicsFunctional selectivityChemistryGlucagon-like peptide 1 receptorMolecular dynamicsCell biologyBiochemistryComputational biologyBiologyStereochemistryComputational chemistryReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyDiabetes Treatment and Management