Definition of fatty acid transport protein-2 (FATP2) structure facilitates identification of small molecule inhibitors for the treatment of diabetic complications
Mukesh Kumar, Robert J. Gaivin, Shenaz Khan, Yuriy Fedorov, Drew Adams, Weiyang Zhao, Hsueh‐Yun Lee, Xinghong Dai, Chris Dealwis, Jeffrey R. Schelling
Topics & Concepts
In silicoVirtual screeningHomology modelingComputational biologyDocking (animal)Drug discoveryPharmacologyChemistrySmall moleculeIC50BiochemistryDiabetes mellitusIn vitroDrugFatty acid-binding proteinFatty acidStructural similarityMedicineBiologyGeneEnzymeEndocrinologyNursingPeroxisome Proliferator-Activated ReceptorsDrug Transport and Resistance MechanismsCannabis and Cannabinoid Research