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Halohydrin dehalogenase-catalysed synthesis of enantiopure fluorinated building blocks: bottlenecks found and explained by applying a reaction engineering approach

Nevena Milčić, Martina Sudar, Irena Dokli, Maja Majerić Elenkov, Zvjezdana Findrik Blažević

2022Reaction Chemistry & Engineering11 citationsDOI

Abstract

Biocatalytic modification of fluorinated styrene oxide derivatives: improvement of reaction outcome in terms of reaction yield, selectivity and product optical purity by employing reaction engineering approach.

Topics & Concepts

Enantiopure drugChemistryComputer scienceOrganic chemistryCatalysisEnantioselective synthesisEnzyme Catalysis and ImmobilizationFluorine in Organic Chemistry
Halohydrin dehalogenase-catalysed synthesis of enantiopure fluorinated building blocks: bottlenecks found and explained by applying a reaction engineering approach | Litcius