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Arctigenin induces activated HSCs quiescence via AMPK-PPARγ pathway to ameliorate liver fibrosis in mice

Mengjia Lv, Shiyi Chen, Mengwen Shan, Yuan Si, Chenggang Huang, Jing Chen, Likun Gong, Likun Gong

2024European Journal of Pharmacology10 citationsDOI

Topics & Concepts

AMPKArctium lappaNatural productLignanFibrosisTraditional medicineAsteraceaeHepatic fibrosisPeroxisome proliferator-activated receptorLiver fibrosisCancer researchChemistryPharmacologyMedicineBiologyBiochemistryProtein kinase AInternal medicinePhosphorylationBotanyGeneStereochemistryLiver physiology and pathologyMacrophage Migration Inhibitory FactorPlant-derived Lignans Synthesis and Bioactivity
Arctigenin induces activated HSCs quiescence via AMPK-PPARγ pathway to ameliorate liver fibrosis in mice | Litcius