Dietary Inflammatory Indices Are Not Associated With Inflammatory Bowel Disease Incidence and Progression
Judith Wellens, Jie Chen, Tian Fu, Yao Zhang, Rahul Kalla, Jack Satsangi, Evropi Τheodoratou, Xue Li
Abstract
Lay Summary Empirical dietary inflammatory pattern and the dietary inflammatory index are dietary inflammation indices, both previously associated with risk of inflammatory bowel disease. We show in the UK Biobank a null association between these indices and incident inflammatory bowel disease; we challenge the current ways in which these dietary indices are derived and interpreted. The need to account for the effects of food processing as well as the raw ingredients is emphasized as a confounding variable.
Topics & Concepts
Inflammatory bowel diseaseMedicineConfoundingIncidence (geometry)Internal medicineDiseaseInflammationGastroenterologyDietary managementUlcerative colitisPhysicsOpticsNutritional Studies and DietConsumer Attitudes and Food LabelingObesity, Physical Activity, Diet