Therapeutic vaccination targeting CD40 and TLR3 controls melanoma growth through existing intratumoral CD8 T cells without new T cell infiltration
Aaron D. Stevens, Timothy N. J. Bullock
Topics & Concepts
CD40Cytotoxic T cellImmunologyCD8Dendritic cellImmunotherapyVaccinationCancer immunotherapyTLR3Immune systemCancer researchT cellPriming (agriculture)MedicineBiologyToll-like receptorInnate immune systemGerminationBiochemistryBotanyIn vitroImmunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersCAR-T cell therapy research