CAR T cells equipped with a fully human scFv targeting Trop2 can be used to treat pancreatic cancer
Hongjia Zhu, Xiaoyan Fang, Israth Jahan Tuhin, Jingwen Tan, Jing Ye, Yujie Jia, Nan Xu, Liqing Kang, Minghao Li, Xiaoyan Lou, Jinge Zhou, Yiting Wang, Zhiqiang Yan, Lei Yu
Topics & Concepts
Chimeric antigen receptorPancreatic cancerCancer researchIn vivoCytotoxic T cellMedicineAntigenIn vitroSingle-chain variable fragmentCancerImmunotherapyImmunologyAntibodyImmune systemInternal medicineBiologyMonoclonal antibodyBiotechnologyBiochemistryCAR-T cell therapy researchMonoclonal and Polyclonal Antibodies ResearchImmunotherapy and Immune Responses