Localized drug delivery graphene bioscaffolds for cotransplantation of islets and mesenchymal stem cells
Mehdi Razavi, Jing Wang, Avnesh S. Thakor
Abstract
< 0.05). Hence, this combination approach of using a graphene bioscaffold that can be functionalized for local delivery of Dex into the surrounding microenvironment, together with AD-MSC therapy, can significantly improve the survival and function of transplanted islets.
Topics & Concepts
Mesenchymal stem cellDrug deliveryStem cellRegenerative medicineCell biologyNanotechnologyMedicineBiologyMaterials scienceGraphene and Nanomaterials ApplicationsPancreatic function and diabetesTissue Engineering and Regenerative Medicine