CD36 and DGAT2 facilitate the lipid-lowering effect of chitooligosaccharides <i>via</i> fatty acid intake and triglyceride synthesis signaling
Xin Shen, Xinyi Liang, Xiaoguo Ji, Jiangshan You, Xinye Zhuang, Yudong Song, Hao Yin, Mengyao Zhao, Liming Zhao
Abstract
acted positively against NAFLD while regulating steatosis in the non-high-fat diet NAFLD model. The potential NAFLD treatment strategies, such as targeting CD36 and DGAT2 signaling, could provide scientific insight into further applying food-derived ingredients to reduce the risk of high-fat metabolism.
Topics & Concepts
CD36TriglycerideLipid metabolismLysophosphatidic acidChemistryMicrosomal triglyceride transfer proteinFatty acidBiochemistryLipid dropletMonoacylglycerol lipaseCholesterolSteatosisEndocrinologyBiologyLipoproteinVery low-density lipoproteinReceptorEndocannabinoid systemLipid metabolism and biosynthesisDiet, Metabolism, and DiseaseAquaculture Nutrition and Growth