Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes
Ruli Gao, Shanshan Bai, Ying C. Henderson, Yiyun Lin, Aislyn Schalck, Yun Yan, Tapsi Kumar, Min Hu, Emi Sei, Alexander Davis, Fang Wang, Simona F. Shaitelman, Jennifer Wang, Ken Chen, Stacy Moulder, Stephen Y. Lai, Nicholas E. Navin
Topics & Concepts
BiologyCopy number analysisComparative genomic hybridizationTranscriptomeCancer researchCopy-number variationCancerKRASComputational biologyGeneGeneticsGene expressionGenomeColorectal cancerSingle-cell and spatial transcriptomicsCancer Genomics and DiagnosticsPancreatic and Hepatic Oncology Research