Reduced intracellular antioxidant capacity in platelets contributes to primary immune thrombocytopenia via ROS-NLRP3-caspase-1 pathway
Shuang Wang, Yang Liu, Guosheng Li, Qi Feng, Ming Hou, Jun Peng
Topics & Concepts
InflammasomePlateletPlatelet activationIntracellularImmunologyPathogenesisImmune thrombocytopeniaMedicineSecretionDownregulation and upregulationImmune systemPharmacologyChemistryInternal medicineInflammationBiochemistryGeneInflammasome and immune disordersPlatelet Disorders and TreatmentsRenal Diseases and Glomerulopathies