Structure−Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists
Ancheng Shen, Xiyuan Li, Yan Zhang, Jing Ma, Ruoxuan Xiao, Xiyuan Wang, Zilan Song, Zhiguo Liu, Meiyu Geng, Ao Zhang, Zuoquan Xie, Chunyong Ding
Topics & Concepts
Stimulator of interferon genesStingChemistryAgonistBenzothiophenePharmacologyIn vivoInterferonStructure–activity relationshipImmunotherapyCancer researchReceptorImmune systemInnate immune systemIn vitroBiochemistryImmunologyMedicineBiologyEngineeringBiotechnologyOrganic chemistryThiopheneAerospace engineeringinterferon and immune responsesCytokine Signaling Pathways and InteractionsImmune Response and Inflammation