In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs
Lei Sun, Pan Li, Xiaohui Ju, Jian Rao, Wenze Huang, Lili Ren, Shaojun Zhang, Tuanlin Xiong, Kui Xu, Xiaolin Zhou, Mingli Gong, Eric A. Miska, Qiang Ding, Jianwei Wang, Qiangfeng Cliff Zhang
Topics & Concepts
BiologyRNACoronavirusSubgenomic mRNAIn silicoCoronaviridaeVirologyComputational biologyUntranslated regionTranslation (biology)GenomeGeneGeneticsMessenger RNACoronavirus disease 2019 (COVID-19)DiseaseInfectious disease (medical specialty)MedicinePathologyinterferon and immune responsesRNA and protein synthesis mechanismsSARS-CoV-2 and COVID-19 Research