Synthesis of methylphosphorylated oligomannosides structurally related to lipopolysaccharide O-antigens of <i>Klebsiella pneumoniae</i> serotype O3 and their application for detection of specific antibodies in rabbit and human sera
A. S. Solov’ev, Evgeniya Denisova, Е. А. Курбатова, Olga Yu. Kutsevalova, Liubov G. Boronina, Vladimir A. Ageevets, Sidorenko Sv, Vadim B. Krylov, Nikolay E. Nifantiev
Abstract
The synthesis and immunochemical application of spacer-armed oligosaccharides related to the outer fragment of the lipopolysaccharide of Klebsiella pneumoniae O3 are reported.
Topics & Concepts
GlycoconjugateBiotinylationChemistryAntibodyOligosaccharideAntigenKlebsiella pneumoniaePolysaccharideSerotypeMicrobiologyBiochemistryEpitopeLipopolysaccharideEscherichia coliBiologyImmunologyGeneCarbohydrate Chemistry and SynthesisGlycosylation and Glycoproteins ResearchPneumocystis jirovecii pneumonia detection and treatment