Antimicrobial peptide-grafted PLGA-PEG nanoparticles to fight bacterial wound infections
António Miguel Ramôa, Filipa Campos, Luis Fernando Moreira, Cátia Teixeira, Victoria Leiro, Paula Gomes, José das Neves, M. Cristina L. Martins, Cláudia Monteiro
Abstract
. Furthermore, NPs do not demonstrate signs of cytotoxicity at MIC concentrations. Overall, this promising formulation helps unleash the full potential of AMPs for the management of wound infections.
Topics & Concepts
Staphylococcus aureusPEG ratioChemistryPseudomonas aeruginosaPLGAAntimicrobialIn vivoPolyethylene glycolPEGylationAntimicrobial peptidesCytotoxicityMicrobiologyThiolIn vitroBiochemistryBacteriaOrganic chemistryBiologyFinanceBiotechnologyEconomicsGeneticsAntimicrobial Peptides and ActivitiesAntimicrobial agents and applicationsPolydiacetylene-based materials and applications