Disulfide Bonds as Functional Tethers in Metal‐Organic Frameworks
Jennifer M. Moore, Douglas T. Genna
Abstract
The functionality of metal-organic frameworks (MOFs) is often encoded by specific chemical moieties found within these architectures. As such, new techniques to install increasingly more complex functionalities in MOFs are regularly being reported in the literature. One such functional group is the disulfide bond. The redox behavior of this covalent linkage renders MOFs responsive to stimuli, often under reducing conditions. Here, we review examples in which disulfide-containing MOFs are deployed in applications including drug delivery, therapeutic ferroptosis, exfoliation, energy storage, sensing, and others.
Topics & Concepts
Disulfide bondMetal-organic frameworkCovalent bondDisulfide LinkageNanotechnologyDrug deliveryMaterials scienceCombinatorial chemistryRedoxChemistryOrganic chemistryCysteineEnzymeBiochemistryAdsorptionMetal-Organic Frameworks: Synthesis and ApplicationsAdvanced Nanomaterials in CatalysisMetal complexes synthesis and properties