A new green approach for the reduction of consumed solvents and simultaneous quality control analysis of several pharmaceuticals using a fast and economic RP-HPLC method; a case study for a mixture of piracetam, ketoprofen and omeprazole drugs
Mohamed A. Abdelgawad, Eglal A. Abdelaleem, Mohammed Gamal, Mohammed A. S. Abourehab, Nessreen S. Abdelhamid
Abstract
the novel method. Also, Memoral® ampoules, Topfam® tablets, and Gastroloc® capsules from Sigma Pharmaceutical Industries, Egypt, could be analyzed simultaneously. Omez® capsules and Ketogesic® tablets from the Pharaonia Pharmaceuticals, Egypt, could be determined simultaneously too. Applying this RP-HPLC method, a significant reduction of the total cost is assured as the required amount of solvent is noticeably decreased when performing multi-analyses in comparison to single component analysis.
Topics & Concepts
Reduction (mathematics)ChemistryChromatographyQuality (philosophy)Control (management)Process engineeringComputer scienceMathematicsArtificial intelligenceEngineeringPhilosophyGeometryEpistemologyChemistry and Chemical EngineeringAnalytical Methods in PharmaceuticalsAnalytical Chemistry and Chromatography