Litcius/Paper detail

Should Inflammation Be a Specifier for Major Depression in the <i>DSM-6</i>?

Manish K. Jha, Marion Leboyer, Carmine M. Pariante, Andrew H. Miller

2025JAMA Psychiatry31 citationsDOI

Abstract

This Viewpoint discusses the opportunity to include inflammatory biomarkers as specifiers for major depression in the upcoming Sixth Edition of the Diagnostic and Statistical Manual of Mental Disorders ( DSM-6 ).

Topics & Concepts

Depression (economics)SpecifierDSM-5PsychologyPsychiatryMajor depressive disorderMental healthMedicineNatural language processingComputer scienceCognitionNoun phraseEconomicsMacroeconomicsNounTryptophan and brain disordersStress Responses and CortisolHealth, psychology, and well-being