Copper-Catalyzed Regiodivergent and Enantioselective Hydrosilylation of Allenes
Jian‐Lin Xu, Zheyuan Xu, Zi‐Lu Wang, W. F. Mader, Xin-Yue Sun, Yao Fu, Yun‐He Xu
Abstract
A copper-catalyzed regiodivergent hydrosilylation of a wide range of simple allenes is reported. Linear and branched allylsilanes were formed by judicious choice of solvents. Furthermore, branched allylsilanes were obtained with high enantioselectivity (up to 97% enantiomeric excess) with the aid of a C2-symmetric bisphosphine ligand in the unprecedented asymmetric allene hydrosilylation.
Topics & Concepts
HydrosilylationChemistryAlleneEnantioselective synthesisEnantiomerCatalysisLigand (biochemistry)Enantiomeric excessCopperOrganic chemistryStereochemistryCombinatorial chemistryReceptorBiochemistryAsymmetric Hydrogenation and CatalysisOrganoboron and organosilicon chemistryCatalytic C–H Functionalization Methods