Litcius/Paper detail

Integrated platform for culture, observation, and parallelized electroporation of spheroids

Pauline Bregigeon, Charlotte Rivière, Laure Franqueville, Christian Vollaire, Julien Marchalot, Marie Frénéa‐Robin

2022Lab on a Chip17 citationsDOIOpen Access PDF

Abstract

We present a new microsystem enabling in vitro culture of hundreds of spheroids in hydrogel support, their monitoring and parallel electroporation. We demonstrate its relevance for electro-chemotherapy assays of increased reproducibility.

Topics & Concepts

ElectroporationSpheroidMicrosystemReproducibilityRelevance (law)In vitroNanotechnologyComputer scienceComputational biologyBiomedical engineeringChemistryEngineeringBiologyMaterials scienceChromatographyBiochemistryGeneLawPolitical scienceMicrobial Inactivation Methods3D Printing in Biomedical ResearchMicrofluidic and Bio-sensing Technologies