Role of carbonate electrolytes on interaction of quinolone drug with anionic surfactant at various temperatures: A conductometric study
Shamim Mahbub, Mohayminul Islam, Abuzayed Masum, Parul Akter, Md. Anamul Hoque, Dileep Kumar, Farah Khan, Malik Abdul Rub, Sulaiman Alfaifi, Abdullah M. Asiri
Abstract
Abstract The role of different carbonate salts on the interaction of anionic surfactant sodium dodecyl sulfate (SDS) with employed quinolone antibiotic drug (ciprofloxacin hydrochloride [CFH]) was explosively inspected through measuring specific conductivity ( κ ) of the investigated system. The drug, CFH, is an excellent antibiotic for the treatment of different bacterial infections like skin, urinary tract, and respiratory infections. The estimated critical micelle concentrations ( cmc ) of SDS were observed to be dwindled in the attendance of electrolytes and cmc reduction continues with the escalation of the electrolyte's concentration. The magnitudes of cmc for the SDS + CFH mixture were reduced with the elevation of temperature in K 2 CO 3 and CaCO 3 medium while increased with the rise of the temperature in the Na 2 CO 3 medium. The magnitudes of counterion binding to micelles ( β ) were increased with the increase of the concentration of Na 2 CO 3 and K 2 CO 3 up to definite value and then reduced with the increase of successive rise of concentration of both salts at all temperatures while decreased monotonically with the rise of electrolyte concentration in CaCO 3 medium. The values of standard free energy ( ) were achieved to be negative in each case suggesting spontaneous self‐assembly formation. The standard entropy change ( ) along with enthalpy change ( ) was also assessed and discussed elaborately.