Effects of bamboo leaf flavonoids on growth performance, antioxidants, immune function, intestinal morphology, and cecal microbiota in broilers
Chao Wu, Hui Ma, Shuwan Lu, Xueyan Shi, Jinsong Liu, Caimei Yang, Ruiqiang Zhang
Abstract
Abstract BACKGROUND Bamboo leaf flavonoids (BLF) are the main bioactive ingredients in bamboo leaves. They have antioxidant, anti‐inflammatory, antibacterial, and other effects. In this study, the effects of dietary BLF on growth performance, immune response, antioxidant capacity, and intestinal microbiota of broilers were investigated. A total of 288 broilers were divided into three groups with eight replicates and 12 birds in each replicate. Broilers were fed a basic diet or the basic diet supplemented with 1000 or 2000 mg kg −1 BLF for 56 days. RESULTS The results showed that supplementation of BLF increased body weight (BW) and average daily weight gain (ADG), and reduced average daily feed intake (ADFI) ( P < 0.05). The serum immunoglobulin A (IgA), immunoglobulin M (IgM), and interleukin 10 (IL‐10) content of broilers in the BLF1000 group was increased and the interleukin 1 β (IL‐1 β ) and tumor necrosis factor‐ α (TNF‐ α ) content was decreased ( P < 0.05). The levels of IgM and IL‐10 in jejunum mucosa were found to be enhanced by BLF ( P < 0.05). The BLF1000 group exhibited a significant reduction in the concentration of TNF‐ α ( P < 0.05). Serum and jejunum mucosa total antioxidant capacity (T‐AOC) levels in the BLF1000 group were increased ( P < 0.05). The serum catalase (CAT) and glutathione peroxidase (GSH‐Px) effects of the BLF1000 group and serum CAT effects of BLF2000 group were increased ( P < 0.05). The CON group demonstrated a lower relative abundance of Christensenellaceae _R‐7_group and Oscillibacter than the BLF group ( P < 0.05). CONCLUSION Dietary BLF inclusion enhanced the growth performance, immune, and antioxidant functions, improved the intestinal morphology, and ameliorated the intestinal microflora structure in broiler. Adding 1000 mg kg −1 BLF to the broiler diet can be considered as an effective growth promoter. © 2024 Society of Chemical Industry.