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Rituximab vs Low-Dose Mycophenolate Mofetil in Recurrence of Steroid-Dependent Nephrotic Syndrome in Children and Young Adults

Pietro Ravani, Francesca Lugani, Stefania Drovandi, Gianluca Caridi, Andrea Angeletti, Gian Marco Ghiggeri

2021JAMA Pediatrics40 citationsDOIOpen Access PDF

Abstract

This randomized clinical trial examines the superiority of a single dose of rituximab vs low-dose mycophenolate mofetil in preventing the recurrence of steroid-dependent nephrotic syndrome in children and young adults.

Topics & Concepts

MedicineMycophenolateRituximabNephrotic syndromeInternal medicinePediatricsYoung adultLymphomaTransplantationRenal Diseases and GlomerulopathiesAutoimmune Bullous Skin DiseasesSystemic Lupus Erythematosus Research