Acrylate-functionalized porphyrin-covalent organic framework for bacterial-targeted and reaction-enhanced synergistic phototherapy/chemotherapy toward sterilization and wound healing
Meng-Chao Wang, Jing-Xuan Guo, Lijian Chen, Xu Zhao
Abstract
a Michael addition reaction, thus fixing the bacteria on the surface of COF and making them lose the colonization ability. Furthermore, the bonding of COF and bacteria further amplifies the therapeutic efficiency of phototherapy. Therefore, the developed multifunctional sterilization platform not only provides a new strategy for the design of novel bactericidal materials but also broadens the biological applications of COF-based materials.
Topics & Concepts
PorphyrinChemistryCovalent bondSterilization (economics)AcrylateWound healingCombinatorial chemistryPhotochemistrySurgeryMedicineOrganic chemistryBusinessExchange rateForeign exchange marketFinancePolymerMonomerNanoplatforms for cancer theranosticsCovalent Organic Framework ApplicationsAdvanced Photocatalysis Techniques