Iron-Catalyzed Thiolation and Selenylation of Cycloalkyl Hydroperoxides via C–C Bond Cleavage
Qing-Xin Sun, He Chen, Shuai Liu, Xiaoqiang Wang, Xin‐Hua Duan, Li‐Na Guo
Abstract
A cheap iron-catalyzed C-C bond cleavage/thiolation and selenylation of cycloalkyl hydroperoxides are presented. This redox-neutral protocol provides efficient access to diverse distal keto-functionalized thioethers and selenium compounds. Remarkably, only some amounts of disulfides are required for this transformation.
Topics & Concepts
ChemistryCleavage (geology)Bond cleavageCatalysisRedoxSeleniumOxidative cleavageCombinatorial chemistryMedicinal chemistryStereochemistryOrganic chemistryGeotechnical engineeringEngineeringFracture (geology)Sulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods