Self-targeting platinum(IV) amphiphilic prodrug nano-assembly as radiosensitizer for synergistic and safe chemoradiotherapy of hepatocellular carcinoma
Xiaohui Xiao, Yupeng Wang, Jieyao Chen, Peng Qin, Peiyao Chen, Dongfang Zhou, Yue Pan
Topics & Concepts
RadiosensitizerCancer researchCisplatinChemoradiotherapyProdrugApoptosisAsialoglycoprotein receptorCell cycleRadiation therapyDNA damageSensitizationHepatocellular carcinomaChemotherapyMaterials sciencePharmacologyMedicineChemistryIn vitroImmunologyInternal medicineBiochemistryDNAHepatocyteNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryRNA Interference and Gene Delivery