Molecular basis for protein–protein interactions
B. Seychell, Tobias Beck
Abstract
This minireview provides an overview on the current knowledge of protein-protein interactions, common characterisation methods to characterise them, and their role in protein complex formation with some examples. A deep understanding of protein-protein interactions and their molecular interactions is important for a number of applications, including drug design. Protein-protein interactions and their discovery are thus an interesting avenue for understanding how protein complexes, which make up the majority of proteins, work.
Topics & Concepts
ChemistryProtein–protein interactionComputational biologyDrug discoveryProtein chemistryBiochemistryBiologyEnzyme Structure and FunctionPhotosynthetic Processes and MechanismsProtein Structure and Dynamics