Litcius/Paper detail

Molecular basis for protein–protein interactions

B. Seychell, Tobias Beck

2021Beilstein Journal of Organic Chemistry29 citationsDOIOpen Access PDF

Abstract

This minireview provides an overview on the current knowledge of protein-protein interactions, common characterisation methods to characterise them, and their role in protein complex formation with some examples. A deep understanding of protein-protein interactions and their molecular interactions is important for a number of applications, including drug design. Protein-protein interactions and their discovery are thus an interesting avenue for understanding how protein complexes, which make up the majority of proteins, work.

Topics & Concepts

ChemistryProtein–protein interactionComputational biologyDrug discoveryProtein chemistryBiochemistryBiologyEnzyme Structure and FunctionPhotosynthetic Processes and MechanismsProtein Structure and Dynamics