Allosteric mutant-selective fourth-generation EGFR inhibitors as an efficient combination therapeutic in the treatment of non-small cell lung carcinoma
Surya Kant Tripathi, Bijesh Kumar Biswal
Topics & Concepts
T790MEpidermal growth factor receptorAllosteric regulationEGFR inhibitorsMutantTyrosine kinaseCancer researchLung cancerOsimertinibPharmacologyDrug resistanceMedicineErlotinibChemistryGefitinibBiologyCancerReceptorOncologyInternal medicineBiochemistryGeneMicrobiologyLung Cancer Treatments and MutationsCancer therapeutics and mechanismsLung Cancer Research Studies