Initial impact of SARS-Cov-2 vaccination on healthcare workers in Italy– Update on the 28th of March 2021
Alberto Mateo‐Urdiales, Martina Del Manso, Xanthi Andrianou, Matteo Spuri, Fortunato D’Ancona, Antonietta Filia, Maria Cristina Rota, Daniele Petrone, Maria Fenicia Vescio, Flavia Riccardo, Antonino Bella, Patrizio Pezzotti, Massimo Fabiani
Abstract
In Italy, the COVID-19 vaccination campaign started in December 2020 with the vaccination of healthcare workers (HCW). To analyse the real-life impact that vaccination is having on this population group, we measured the association between week of diagnosis and HCW status using log-binomial regression. By the week 22-28 March, we observed a 74% reduction (PPR 0.26; 95% CI 0.22-0.29) in the proportion of cases reported as HCW and 81% reduction in the proportion of symptomatic cases reported as HCW, compared with the week with the lowest proportion of cases among HCWs prior to the vaccination campaign (31 August-7 September). The reduction, both in relative and absolute terms, of COVID-19 cases in HCWs that started around 30 days after the start of the vaccination campaign suggest that COVID-19 vaccines are being effective in preventing infection in this group.