Na <sup>+</sup> -dependent gate dynamics and electrostatic attraction ensure substrate coupling in glutamate transporters
Claudia Alleva, Kirill Kovalev, Roman Astashkin, M. Berndt, Christian Baeken, Taras Balandin, Valentin Gordeliy, Christoph Fahlke, Jan‐Philipp Machtens
Abstract
:substrate transport stoichiometry over a broad range of neurotransmitter concentrations.
Topics & Concepts
Glutamate receptorSubstrate (aquarium)Molecular dynamicsBiophysicsIonTransporterChemistryAmino acidGlutamic acidCrystallographyBiochemistryBiologyComputational chemistryGeneReceptorOrganic chemistryEcologyNeuroscience and Neuropharmacology ResearchMolecular Sensors and Ion DetectionAdvanced biosensing and bioanalysis techniques