Aberrant TRPM4 expression in MLL-rearranged acute myeloid leukemia and its blockade induces cell cycle arrest via AKT/GLI1/Cyclin D1 pathway
Fujue Wang, Pengqiang Wu, Shuaige Gong, Yingying Chen, Jie Gao, Shuoting Wang, Qianqing Shen, Huan Tao, Fang Hua, Zhencang Zhou, Zhongqing Zou, Tao Ma, Yongqian Jia
Topics & Concepts
Cancer researchCell cycleMyeloid leukemiaCyclin D1LeukemiaGLI1BiologyTranscription factorProtein kinase BGene knockdownCell cycle checkpointCell cultureSignal transductionCellImmunologyGeneCell biologyGeneticsInsect Resistance and GeneticsPlant Reproductive BiologyCoagulation, Bradykinin, Polyphosphates, and Angioedema