Editorial: The emerging role of metabolism and metabolic-related receptors on neutrophil extracellular traps (NET) formation

Abstract

The emerging role of metabolism and metabolic-related receptors on neutrophil extracellular traps formation Neutrophils play a central role in host innate immunity as first cell line to fight pathogens; however, they are also being responsible for "collateral damage". Neutrophils have a wide repertoire of biological responses, including reactive oxygen species (ROS)dependent and -independent effector mechanisms. Release of neutrophil extracellular traps (NET) has been added as key innate immune reaction. Understanding NET formation has broadened our knowledge regarding innate defence mechanisms as well as pathological mechanisms associated with occurrence of uncontrolled NET.

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