Tanshinone IIA protected against lipopolysaccharide-induced brain injury through the protective effect of the blood–brain barrier and the suppression of oxidant stress and inflammatory response
Xin Wang, Wei-Mei Wang, Hao Han, Yu Zhang, Jinling Liu, Jiaying Yu, Huimin Liu, Xingtong Liu, Hu Shan, Shuai-Cheng Wu
Abstract
Tanshinone IIA protected against lipopolysaccharide-induced brain injury through the protective effect of blood-brain barrier and the suppression of oxidant stress and inflammatory response.
Topics & Concepts
LipopolysaccharideBlood–brain barrierInflammatory responsePharmacologyBrain damageInflammationMedicineChemistryImmunologyCentral nervous systemEndocrinologyInternal medicineTraditional Chinese Medicine AnalysisNeuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies