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NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production

Yiting Cai, Yue Zhu, Jiaqi Zheng, Yuchuan Zhang, Wei Chen

2022Biochemical and Biophysical Research Communications14 citationsDOI

Topics & Concepts

IRF3AutophagyInterferonInterferon regulatory factorsCell biologyBiologySendai virusUbiquitinSignal transductionProtein degradationVirusReceptorVirologyBiochemistryInnate immune systemGeneApoptosisinterferon and immune responsesAutophagy in Disease and TherapyCytomegalovirus and herpesvirus research
NBR1 mediates autophagic degradation of IRF3 to negatively regulate type I interferon production | Litcius